I-HPMC Hydroxypropyl methylcellulose, eyaziwa nangokuthi i-hypromellose, ingenye ye-non-ionic cellulose exubile ethers.Kuyi-semi-synthetic, engasebenzi, i-viscoelastic polymer evame ukusetshenziswa njengesithambisi ku-ophthalmology, noma njengesamukeli noma isamukeli emithini yomlomo.
Igama lomkhiqizo iHydroxypropyl methyl cellulose(HPMC)
Elinye igama iHydroxypropyl methylcellulose,MHPC, methyl Hydroxypropyl cellulose
Inombolo Yokubhalisa ye-CAS 9004-65-3
Ukubukeka okumhlophe kwe-fibrous noma i-granular powder
incazelo yokuphepha S24/25
Izakhiwo zomzimba namakhemikhali
Ukubukeka: impushana emhlophe noma ecishe ibe mhlophe noma i-granular
Ukuzinza: Izinto eziqinile ziyavutha futhi azihambisani nama-oxidants aqinile.
Imbudumbudu;Izinga lokuphasa lika-100 mesh libe ngaphezu kwama-98.5%.Izinga lokuphasa kwamehlo angama-80 liyi-100%.Usayizi okhethekile wosayizi wezinhlayiyana 40 ~ 60 mesh.
Ukushisa kwe-Carbonization: 280-300 ℃
Ukuminyana okubonakalayo: 0.25-0.70g/cm3 (imvamisa cishe ku-0.5g/cm3), amandla adonsela phansi athile 1.26-1.31.
Ukushisa okushintsha umbala: 190-200 ℃
Ukushuba kobuso: 42-56dyne/cm kusixazululo samanzi esingu-2%.
Ukunyibilika: ukuncibilika emanzini nakwezinye izincibilikisi, njengengxenye efanele ye-ethanol/amanzi, i-propanol/amanzi, njll. Isixazululo esinamanzi sinomsebenzi ongaphezulu.Ukucaca okuphezulu, ukusebenza okuzinzile, ukucaciswa okuhlukile kokushisa kwejeli komkhiqizo kuhlukile, izinguquko zokuncibilika ne-viscosity, i-viscosity ephansi, ukuncibilika okukhulu, ukucaciswa okuhlukile kokusebenza kwe-HPMC kunomehluko othile, isisombululo se-HPMC emanzini asithinteki Inani le-pH.
Umsebenzi ongaphezulu we-HPMC wehla ngokuncipha kokuqukethwe kwe-methoxyl, ukwanda kwephoyinti lejeli kanye nokuncipha kokuncibilika kwamanzi.
I-HPMC futhi inekhono lokuqina, ukumelana nosawoti okuphansi komlotha owumpushana, ukuzinza kwe-pH, ukugcinwa kwamanzi, ukuzinza kwe-dimensional, ukwakheka kwefilimu okuhle kakhulu, kanye nohlu olubanzi lokumelana ne-enzyme, ukuhlakazeka kanye nezici zokubopha.
Izindlela zokukhiqiza
I-cellulose kakotini ecolisisiwe iphathwa nge-lye ku-35-40℃ isigamu sehora, icindezelwe, i-cellulose igaywe futhi iguge ku-35℃, ukuze idigri ye-polymerization emaphakathi yefayibha ye-alkali etholiwe ibe ngaphakathi kwebanga elidingekayo.Faka i-alkali fibre eketelani le-etherification, engeza i-propylene oxide ne-methane chloride ngokulandelana, i-etherize ku-50-80℃ amahora angu-5, ukucindezela okuphezulu cishe ku-1.8mpa.Bese wengeza inani elifanele le-hydrochloric acid ne-oxalic acid yokugeza izinto emanzini ashisayo angama-90 ℃ ukuze ukhulise ivolumu.Lapho okuqukethwe kwamanzi kumpahla kungaphansi kwama-60%, omiswa abe ngaphansi kuka-5% ngokugeleza komoya oshisayo ku-130 ℃.Ekugcineni, umkhiqizo oqediwe uchotshozwa futhi uhlolwe nge-mesh engu-20.
Indlela yokuhlakaza
I-1, wonke amamodeli angangezwa kundaba ngendlela yokuxuba okomile.
I-2, idinga ukungezwa ngokuqondile kwisisombululo samanzi okushisa okujwayelekile, kungcono ukusebenzisa ukuhlakazeka kwamanzi abandayo, emva kokungeza ngokuvamile emaminithini angu-10-90 ukushuba.
3. Amamodeli avamile angancibilika ngemva kokuxuba nokuhlakazwa ngamanzi ashisayo bese wengeza amanzi abandayo ngemva kokuhlanganisa nokupholisa.
4. Uma kuqedwa, uma kwenzeka i-agglomerating, kungenxa yokuthi ukuxuba akwanele noma amamodeli ajwayelekile afakwa ngokuqondile emanzini abandayo.Ngalesi sikhathi, kufanele ixutshwe ngokushesha.
5. Uma ama-bubbles eyenzeka ngesikhathi sokuchithwa, angasuswa ngokuma amahora angu-2-12 (isikhathi esiqondile sincike ekuvumelaneni kwesixazululo) noma ngokufaka i-vacuumizing kanye nokucindezela, noma ngokungeza inani elifanele le-ejenti yokukhipha amagwebu.
I-HPMC isebenzisa
Isetshenziswa njenge-thickener, dispersant, binder, exciphant, i-oyela ukumelana nowoyela, i-filler, i-emulsifier kanye ne-stabilizer embonini yendwangu.Ibuye isetshenziswe kabanzi kuma-synthetic resin, i-petrochemical, i-ceramic, iphepha, isikhumba, imithi, ukudla nezimonyo nezinye izimboni.
Inhloso eyinhloko
1, imboni yezokwakha: njenge-ejenti yokugcinwa kwamanzi kasimende, i-retarder nodaka ngokumpompa.Ekukhometheni, i-gypsum, i-putty powder noma ezinye izinto zokwakha njenge-adhesive, thuthukisa i-daub futhi andise isikhathi sokusebenza.Isetshenziselwa ukunamathisela ithayela le-ceramic, imabula, umhlobiso wepulasitiki, i-ejenti yokuqinisa unamathisele, isenganciphisa umthamo usimende.Ukusebenza kokugcinwa kwamanzi kwe-HPMC kwenza i-slurry ngemva kokufaka isicelo ngeke ibe ngenxa yokoma ngokushesha okukhulu nokuqhekeka, kuthuthukise amandla ngemva kokuqina.
2, ukukhiqizwa kwe-ceramic: kusetshenziswa kabanzi njenge-adhesive ekukhiqizeni umkhiqizo we-ceramic.
I-3, imboni yokuhlanganisa: embonini yokumboza njenge-thickener, dispersant kanye ne-stabilizer, emanzini noma ku-organic solvents kune-solubility enhle.Njengesikhiphi sikapende.
I-4, ukuphrinta kwe-inki: embonini ye-inki njenge-thickener, dispersant kanye ne-stabilizer, emanzini noma izincibilikisi eziphilayo zine-solubility enhle.
5, ipulasitiki: ukwakha i-ejenti yokukhululwa, isithambisi, okokugcoba, njll.
I-6, i-PVC: Ukukhiqizwa kwe-PVC njenge-dispersant, ukulungiswa kwe-polymerization yokumiswa kwezinsiza eziyinhloko ze-PVC.
7, embonini yezemithi: izinto zokugqoka;Impahla ye-membrane;Izinto ze-polymer ezilawulwa isilinganiso sokulungiselela ukukhishwa okuqhubekayo;I-ejenti yokuzinzisa;Usizo olumisiwe;Ukunamathela kwethebhulethi;Yandisa i-goo
I-8, Abanye: futhi isetshenziswa kabanzi embonini yesikhumba, yemikhiqizo yephepha, ukulondolozwa kwezithelo nemifino kanye nomkhakha wezindwangu.
Uhlelo lokusebenza lwemboni ethile
Imboni yezokwakha
1, usimende nosimende: ngcono ukuhlakazwa usimende - isihlabathi, ngcono kakhulu plasticity kanye nokugcinwa kwamanzi nodaka, ukuvimbela imifantu nomthelela, kungathuthukisa amandla usimende.
2, usimende wethayela le-ceramic: thuthukisa ipulasitiki yodaka lwe-ceramic tile, ukugcinwa kwamanzi, uthuthukise i-glue relay ye-ceramic tile, uvimbele impushana.
I-3, i-asbestos nokunye ukunamathela okuphikisayo: njenge-ejenti yokumiswa, i-ejenti yokuthuthukisa i-liquidity, kodwa futhi ithuthukise isisekelo se-glue edluliselwe.
I-4, i-gypsum slurry: thuthukisa ukugcinwa kwamanzi nokucutshungulwa, thuthukisa ukunamathela kwesisekelo.
5, usimende ohlangene: engeza ebhodini le-gypsum ngosimende ohlangene, uthuthukise uketshezi kanye nokugcinwa kwamanzi.
I-6, i-latex putty: thuthukisa i-fluidity nokugcinwa kwamanzi kwe-resin latex putty esekelwe.
I-7, udaka: njengengxenye yokunamathisela kwemvelo, ingathuthukisa ukugcinwa kwamanzi, ithuthukise i-glue edluliselwe ngesisekelo.
I-8, i-coating: njenge-plasticizer ye-latex coating, inendima ekuthuthukiseni ukusebenza kokusebenza kanye nokumanzi kwe-coating kanye ne-putty powder.
I-9, i-spray coating: ukuvimbela usimende noma i-latex yokufafaza kuphela ukucwiliswa kwezinto ezibonakalayo nokuthuthukisa ukugeleza nokufutha ihluzo ze-beam kunomphumela omuhle.
10, usimende, Gypsum imikhiqizo yesibili: njengoba usimende - asbestos nezinye izinto wokubacindezela ngokucindezela ukubumba binder, ngcono fluidity, angathola imikhiqizo ukubumba umfaniswano.
11, i-fiber wall: ngenxa yomphumela wokulwa namagciwane, njengoba isibopho sodonga lwesihlabathi sisebenza kahle.
I-12, enye: ingasetshenziswa njengodaka oluncane oluncane kanye nendima yomqhubi wodaka we-ejenti ephethe ibhamuza.
Imboni yamakhemikhali
1, i-vinyl chloride, i-vinyl polymerization: njenge-polymerization suspension stabilizer, dispersant, ne-vinyl alcohol (PVA) i-hydroxypropyl cellulose (HPC) futhi ingalawula ukusatshalaliswa komumo wezinhlayiyana nezinhlayiyana.
I-2, ingcina: njenge-adhesive yamaphephadonga, esikhundleni sesitashi ngokuvamile ingasetshenziswa nge-vinyl acetate latex coating.
3. I-Pesticide: yengezwe kuma-insecticides nama-herbicides, ingathuthukisa umphumela wokunamathela lapho ufutha.
4, i-latex: thuthukisa i-asphalt emulsion stabilizer, irabha ye-styrene butadiene (SBR) i-latex thickener.
5, isibopho: njengepensela, ikhrayoni eyakha ingcina.
Imboni yezimonyo
1. I-Shampoo: thuthukisa i-viscosity nokuzinza kwamabhamuza we-shampoo, okokuhlanza kanye ne-detergent.
2. Isixubho: Thuthukisa ukugcwala komuthi wokuxubha.
Imboni yokudla
1, i-citrus ekheniwe: vimbela ekulondolozweni ngenxa yokubola kwe-orange glycosides kanye ne-metamorphism emhlophe ukuze uzuze ubusha.
2, imikhiqizo yezithelo ezibandayo: engeza izithelo zamazolo, i-ice medium, yenza ukunambitheka kube ngcono.
3, isoso: njengesoso, i-tomato sauce emulsifying stabilizer noma i-ejenti yokuqina.
4, ukucwebezela kwamanzi abandayo: okusetshenziselwa ukugcinwa kwezinhlanzi eziqandisiwe, kungavimbela ukushintsha kombala, ukuncipha kwekhwalithi, nge-methyl cellulose noma i-hydroxypropyl methyl cellulose isisombululo esicwebezelisiwe, bese siqandiswa eqhweni.
I-5, i-adhesive yamaphilisi: njenge-adhesive yokwakha yamaphilisi namaphilisi, ukubopha nokugoqa (chiza ngokushesha futhi uhlakaze lapho uthatha) kuhle.
Imboni yezemithi
1. I-Coating: i-ejenti yokugqoka yenziwa isixazululo se-solvent ephilayo noma isisombululo samanzi samaphilisi, ikakhulukazi izinhlayiya ezenziwe nge-spray coating.
2, i-ejenti yehlisa ijubane: 2-3 amagremu ngosuku, isikhathi ngasinye umthamo we-1-2G, ngezinsuku ezingama-4-5 ukukhombisa umphumela.
I-3, umuthi wamehlo: ngoba ingcindezi ye-osmotic ye-hydroxypropyl methyl cellulose isixazululo samanzi ifana nezinyembezi, ngakho-ke incane emehlweni, engeza umuthi wamehlo, njenge-lubricant ukuze uxhumane ne-eyeball lens.
I-4, i-gelatinous ejenti: njengesisekelo somuthi wangaphandle we-gelatinous noma wamafutha.
I-5, isidakamizwa esimithiyo: njenge-ejenti yokuqina, i-ejenti yokugcina amanzi.
Imboni yomlilo
1, izinto ze-elekthronikhi: njenge-ceramic denser kagesi, i-bauxite ferrite i-magnetic compression molding adhesive, ingasetshenziswa ne-1.2-propylene glycol.
I-2, i-glaze: esetshenziswa njenge-ceramic glaze kanye ne-porcelain enoqweqwe lwawo, ingathuthukisa ukubopha nokucutshungulwa.
I-3, i-refractory mortar: engeza ngodaka oluphikisayo noma impahla yesithando somlilo, ingathuthukisa ipulasitiki nokugcinwa kwamanzi.
Ezinye izimboni
I-1, i-fiber: njengokuphrinta udayi wokunamathisela we-pigments, odayi behlathi le-boron, odayi abasuselwe kusawoti, odayi bezindwangu, ngaphezu kwalokho, ekucubunguleni kwe-kapok ripple, ingasetshenziswa ne-resin eqinisa ukushisa.
2, iphepha: elisetshenziselwa ukunamathiswa kwesikhumba se-carbon paper kanye nokucubungula uwoyela nezinye izici.
3, Isikhumba: njengoba okokugcina kokugcoba noma ukusetshenziswa okunamathelayo okulahlwayo.
4, uyinki osuselwe emanzini: wengezwe kuyinki osuselwe emanzini, uyinki, njenge-ejenti yokuqina, i-ejenti yokwakha ifilimu.
5, ugwayi: njengento enamathelayo kagwayi ogaywe kabusha.
I-Pharmacopoeia ejwayelekile
Umthombo nokuqukethwe
Lo mkhiqizo yi-2- hydroxypropyl ether methyl cellulose.IHydroxypropyl methylcellulose ingahlukaniswa ngezinhlobo ezine ngokuya ngokuqukethwe kwe-methoxy ne-hydroxypropyl, okuyi-1828, 2208, 2906, 2910. Okuqukethwe kwe-methoxy ngayinye efakwe endaweni (-OCH3) kanye ne-hydroxypropoxy (-OCH2ChohCH3) kufanele kuhambisane nezinhlinzeko ezinamathiselwe itafula.
uhlamvu
Lo mkhiqizo une-fibrous emhlophe noma i-quasi-white noma i-granular powder;Ayinaphunga.
Lo mkhiqizo cishe awuncibiliki ku-ethanol anhydrous, ether kanye ne-acetone;Ukuvuvukala emanzini abandayo ukwenza isixazululo se-colloid esicacile noma esincane.
Ukukhomba
(1) Thatha u-1g womkhiqizo, shisisa u-100mL wamanzi (80 ~ 90℃), gudluza ngokuqhubekayo, uphole endaweni yokugeza eqhweni, bese wenza uketshezi olunamathelayo;Faka u-2mL wekhambi eshubhuni yokuhlola, kancane wengeze u-1mL ka-0.035% wesisombululo se-anthracene sulfuric acid eduze kodonga lweshubhu, uyibeke imizuzu emi-5, bese kuvela indandatho eluhlaza okwesibhakabhaka esibonakalayo phakathi kwalezi ziphuzo ezimbili.
(2) Inani elifanele loketshezi lwe-viscous ngaphansi kokuhlonza (1) lithelwa epuleti lengilazi.Ngemva kokuhwamuka kwamanzi, kwakheka ungqimba lwefilimu eqinile.
hlola
1, ph
Ngemuva kokupholisa, lungisa ikhambi libe ngu-100g ngamanzi bese ugoqa kuze kube yilapho lichithwa ngokuphelele.Nquma ngokomthetho (Isithasiselo ⅵ H, Ingxenye II ye-Pharmacopoeia, uhlelo lwango-2010).PH inani kufanele libe ngu-5.0-8.0.
2, i-viscosity
Ukumiswa okungu-2.0% (g/g) kwalungiswa ngokuthatha u-10.0g womkhiqizo nokungeza amanzi angama-90℃ ukwenza isisindo esiphelele sesampula namanzi sibe ngu-500.0g njengomkhiqizo owomile.Ukumiswa kwashukunyiswa ngokugcwele cishe imizuzu eyi-10 kuze kube yilapho izinhlayiya zihlakazeka ngokuphelele futhi zimanzi.Ukumiswa kwapholiswa endaweni yokugezela eqhweni futhi kwaqhubeka nokunyakaza imizuzu engu-40 phakathi nenqubo yokupholisa.I-viscosimeter ye-cylinder rotary eyodwa (i-ndJ-1 ingasetshenziselwa amasampula ane-viscosity engaphansi kuka-100Pa·s, futhi i-NDJ-8S ingasetshenziselwa amasampula ane-viscosity enkulu noma elingana no-100Pa·s, noma enye i-viscosimeter efanelekayo efanelekayo) isetshenziswe kokuthi 20℃±0.1℃, inqunywe ngokuvumelana nomthetho (indlela yesibili ye-ⅵ G ku-appendix II ye-Pharmacopoeia 2010 edition).Uma i-viscosity enelebula ingaphansi kuka-600mPa·s, i-viscosity kufanele ibe ngu-80% ~ 120% we-viscosity enelebula;Uma i-viscosity enelebula ingaphezu noma ilingana no-600mPa·s, i-viscosity kufanele ibe ngu-75% kuya ku-140% we-viscosity enelebula.
3 Into engancibiliki emanzini
Thatha u-1.0g womkhiqizo, uwubeke ebhekhani, engeza amanzi ashisayo angu-100mL ku-80-90 ℃, uvuvuke cishe imizuzu engu-15, uyipholise endaweni yokugeza eqhweni, engeza amanzi angu-300mL (uma kunesidingo, ukwandisa umthamo wamanzi ngokufanele qinisekisa ukuthi ikhambi liyahlungwa), futhi uligoqe ngokugcwele, lihlunge ngo-no.I-crucible yengilazi encibilikayo eqondile engu-1 eyomiswa ukuze ibe nesisindo esingaguquki esingu-105℃, bese uhlanza ibhika ngamanzi.Uketshezi lwahlungwa ku-crucible yengilazi encibilikayo engenhla futhi yomiswa ukuze ibe nesisindo esingashintshi esingu-105℃, nensalela engeqile ku-5mg (0.5%).
4 Ukwehla kwesisindo okomile
Thatha lo mkhiqizo futhi uwomise ku-105℃ amahora angu-2, futhi ukuncipha kwesisindo ngeke kudlule u-5.0% (Isithasiselo ⅷ L, Ingxenye II, i-Pharmacopoeia 2010 edition).
5 Ukushisa izinsalela
Thatha u-1.0g walo mkhiqizo futhi uwuhlole ngokomthetho (Isithasiselo ⅷ N, Ingxenye II ye-pharmacopoeia 2010 edition), futhi okusele akumele kudlule u-1.5%.
6 insimbi enzima
Thatha okusele kwesokunxele ngaphansi kwezinsalela ze-incandescent, hlola ngokuhambisana nomthetho (indlela yesibili yeSithasiselo ⅷ H yengxenye yesibili ye-pharmacopoeia ka-2010), equkethe izinsimbi ezinzima akufanele idlule izingxenye ezingu-20 ngesigidi.
7 usawoti we-arsenic
Thatha u-1.0g walo mkhiqizo, engeza u-1.0g we-calcium hydroxide, uhlanganise, engeza amanzi ukuze ugovuze ngokulinganayo, womile, kuqala ngomlilo omncane ukuze u-carbonize, bese ku-600 ℃ ukushisa umlotha ngokuphelele, ukupholisa, engeza i-5mL hydrochloric acid kanye namanzi angu-23mL. ukuhlakaza, hlola ngokomthetho (2010 edition of pharmacopoeia ii Isithasiselo ⅷ J indlela yokuqala), kufanele ihambisane nezinhlinzeko (0.0002%).
Ukuzimisela kokuqukethwe
1, i-methoxyl
I-Methoxy, ethoxy ne-hydroxypropoxy (i-appendix VII F, Ingxenye II, Ushicilelo luka-2010 lwe-Pharmacopoeia) kwanqunywa.Uma indlela yesibili (indlela ye-volumetric) isetshenziswa, thatha umkhiqizo, ukale ngokunembile futhi ulinganise ngokomthetho.Inani le-methoxy elilinganisiwe (%) lidonswa emkhiqizweni wenani le-hydroxypropoxy (%) kanye (31/75×0.93).
2, i-hydroxypropoxy
I-Methoxy, ethoxy ne-hydroxypropoxy (i-appendix VII F, Ingxenye II, Ushicilelo luka-2010 lwe-Pharmacopoeia) kwanqunywa.Uma indlela yesibili (indlela yevolumu) isetshenziswa, thatha umkhiqizo cishe u-0.1g, ukale ngokunembile, unqume ngokomthetho, futhi uthole.
I-Pharmacology kanye ne-toxicology
IHydroxypropyl methyl cellulose iyingxenye ye-cellulose methyl futhi iyingxenye ye-hydroxypropyl ether, ingancibilika emanzini abandayo ukuze yakhe isixazululo se-viscous, izakhiwo zayo kanye nezinyembezi ezintweni ze-viscoelastic (ikakhulukazi i-mucin) eseduze, ngakho-ke, ingasetshenziswa njenge-artificial. izinyembezi.Indlela yokusebenza ukuthi i-polymer inamathela ebusweni beso ngokusebenzisa i-adsorption, ilingisa isenzo se-conjunctival mucin, ngaleyo ndlela ithuthukise isimo sokunciphisa i-ocular mucin futhi ikhulise ubude besikhathi sokugcinwa kwamehlo esimweni sokunciphisa izinyembezi.Lokhu kukhangisa kuzimele ku-viscosity yesisombululo futhi ngaleyo ndlela kuvumela umphumela wokumanzisa okuhlala njalo ngisho nezixazululo eziphansi ze-viscosity.Ukwengeza, ukumanzisa i-corneal kuyanda ngokunciphisa i-Engeli yokuthintana nendawo ehlanzekile yekhone.
i-pharmacokinetics
Ayikho idatha ye-pharmacokinetic ebikiwe ngokusetshenziswa kwezihloko zalo mkhiqizo.
izinkomba
Monisa amehlo ngokungakhihli kwezinyembezi futhi uqede ukungaphatheki kahle kwamehlo.
Ukusetshenziswa
Bobabili abadala kanye nezingane bangayisebenzisa.1-2 amaconsi, kathathu ngosuku;Noma njengoba eyalelwe udokotela.
Ukusabela okubi hlela inkulumo
Ezimweni ezingavamile kungase kubangele ukungaphatheki kahle kwamehlo njengobuhlungu bamehlo, ukungaboni kahle, ukuminyana kwe-conjunctival okuqhubekayo noma ukucasuka kweso.Uma izimpawu ezingenhla zisobala noma ziphikelela, yeka ukusebenzisa umuthi uye esibhedlela uyohlolwa.
ihlazo
I-Contraindicated kubantu abangezwani nalo mkhiqizo.
Izindaba ezidinga ukunakwa
1. Ungathinti ikhanda lebhodlela lokudonsa enkopheni nakwezinye izindawo ukuze uvimbele ukungcola
2. Sicela ugcine umkhiqizo lapho izingane zingafinyeleleki khona
3. Inyanga eyodwa ngemva kokuvula ibhodlela, akufanelekile ukuqhubeka nokuyisebenzisa.
4. Imithi yabesifazane abakhulelwe nabancelisayo: akukho mibiko yokulimala kokuzala noma ezinye izinkinga ezibangelwa i-HYDROXYpropyl cellulose emzimbeni womuntu;Akukho ukusabela okubi okuye kwabikwa ezinganeni ngesikhathi sokuncelisa.Ngakho-ke, akukho ukuphikisana okukhethekile kwabesifazane abakhulelwe nabancelisayo.
5. Imithi yezingane: uma kuqhathaniswa namanye amaqembu eminyaka yobudala, i-hydroxypropyl methylcellulose ezinganeni ayibangeli ukusabela okubi kakhulu.Ngakho-ke, izingane kanye nabantu abadala bangasebenzisa lo mkhiqizo ngokohlelo olufanayo.
6, imithi yabantu asebekhulile: ukusetshenziswa kwe-hydroxypropyl methylcellulose ezigulini esezikhulile, uma kuqhathaniswa namanye amaqembu eminyaka, akubangeli imiphumela emibi ehlukene noma ezinye izinkinga.Ngakho-ke, umuthi wesiguli esikhulile awunakho ukuphikisana okukhethekile.
7, isitoreji: isitoreji esingangenisi.
Ukusebenza kokuphepha
Ingozi yezempilo
Lo mkhiqizo uphephile futhi awunabo ubuthi, ungasetshenziswa njengesengezo sokudla, akukho ukushisa, akukho ukucasuka kwesikhumba kanye nolwelwesi lwamafinyila ukuthintana.Ngokuvamile kubhekwa njengephephile (FDA1985).Umthamo wansuku zonke ovunyelwe ngu-25mg/kg (FAO/WHO 1985).Izinto zokuzivikela kufanele zigqokwe ngesikhathi sokusebenza.
Umthelela kwezemvelo
Gwema ukungcoliswa komoya okubangelwa ukundiza kothuli.
Izingozi ezingokomzimba namakhemikhali: gwema ukuthintana nemithombo yomlilo, futhi gwema ukwenza uthuli oluningi endaweni evaliwe ukuze uvimbele izingozi eziqhumayo.
Izinto zesitolo zithunyelwe
Naka ukuvikelwa kwelanga emvuleni nasemanzini, gwema ilanga eliqondile, elivalwe endaweni eyomile.
Isikhathi sokuphepha
I-S24/25: Gwema ukuthintana nesikhumba namehlo.
Gwema ukuthinta isikhumba namehlo.
Isikhathi sokuthumela: Dec-02-2021