Okungcono, CMC noma i-HPMC?

Ukuqhathanisa ngempumelelo nokuhlola i-CMC (i-carboxymethyl celtulose) ne-HPMC (i-hpdroxypropyl methylcellulose), kudingeka sicabangele izakhiwo zabo, izinhlelo zokusebenza, izinzuzo, izinto ezingezinhle, kanye nokufanelekela ngezinhloso ezahlukahlukene. Kokubili i-CMC ne-HPMC kuma-cellulose decivativeveveveveves esetshenziswa kabanzi kwizimboni ezahlukahlukene, kufaka phakathi ama-Pharmaceuticals, ukudla, izimonyo kanye nokwakha. Ngamunye unezimpawu zawo ezihlukile nezinzuzo, ezinquma ukufaneleka kwazo kwezicelo ezithile.

1. Isingeniso ku-CMC ne-HPMC:

I-Carboxymethyl Cellulose (CMC):
I-CMC iyi-cellulose esuselwa emanzini asuselwa ku-cellulose yemvelo ngokwazisa amaqembu e-carboxymethyl e-cellulose backbone. Isetshenziswa kakhulu njenge-ejenti ekhuthele, i-stabilizer, ne-ejenti yokugcinwa kwamanzi emikhakheni ehlukahlukene.

I-Hydroxypropyl methylcellulose (HPMC):
I-HPMC kungenye into etholwa ngamanzi ekhiqizwayo ekhiqizwa ukwelapha i-cellulose nge-propelene oxide ne-methyl chloride. Ithola izinhlelo zokusebenza emikhakheni, ekudleni, izimonyo, kanye nokwakha ngenxa yokuqina kwayo, ukwakha amafilimu, kanye nokubopha izakhiwo.

2. Izakhiwo eziqhathaniswa:

I-Solubity:
I-CMC: incane ngokuphelele emanzini.
I-HPMC: incibilika emanzini ngaphansi kwezimo ezithile, yakha isisombululo esicacile noma esincanyana.

I-Viscosity:
I-CMC: Ibonisa i-viscosity ephezulu ngisho nokugxila okuphansi.
I-HPMC: I-Viscosity iyahlukahluka ngokuya ngezinga lokufakwa esikhundleni kanye nesisindo se-molecular.

Izakhiwo ezenziwe ngefilimu:
I-CMC: Ikhono elilinganiselwe lefilimu.
I-HPMC: Izakhiwo ezinhle kakhulu zefilimu, okwenza zilungele izinhlelo zokusebenza ezinjengezimbobo namafilimu.

Ukuqina okushisayo:
I-CMC: Ngokuvamile ukuqina okuphansi okuphansi kuqhathaniswa ne-HPMC.
I-HPMC: Ibonisa ukuqina okungcono okushisayo, okwenza kube lula ukuthola izicelo eziphezulu zokushisa.

I-3.Application:

Izicelo ze-CMC:
Imboni yokudla: Isetshenziswa njenge-ejenti yokuqina, i-Stabilizer, kanye ne-ajenti yokugcinwa komswakama kwimikhiqizo efana namasoso, ukugqoka, kanye nemikhiqizo yobisi.
Izemithi: Kuqashwe ekusungulweni kwethebhulethi njenge-binder nokuqhekeka.
Imikhiqizo yokunakekelwa komuntu siqu: Itholakala kumazinyo, okhilimu, ama-lotion kanye nezimonyo njenge-smighter kanye ne-stabilizer.
Ukushayela uwoyela: kusetshenziswe ku-dripling fluids ukulawula i-viscosity kanye nokulahleka koketshezi.

Izicelo ze-HPMC:
Imboni yezokwakha: Isetshenziswa odongeni osuselwa kusawoti, ama-Plasters, kanye nama-tile anamathela ukuze athuthukise ukusebenziseka kanye nokunamathela.
Imboni yezemithi: Iqashwe ezinhlelweni zokukhishwa kwezidakamizwa ezilawulwayo, ukumbona ithebhulethi, kanye nezixazululo ze-ophthalmic.
Imboni yokudla: Isetshenziswa njenge-persener, emulsifier, kanye ne-stabilizer emikhiqizweni efana nezimpahla zokubhaka nemikhiqizo yobisi.
Izimonyo: ezitholakala kwimikhiqizo efana nama-shampoos, okhilimu, kanye ne-lotions njenge-ejenti ekhuthele kanye nefilimu yangaphambili.

4. Izinzuzo nobubi:

Izinzuzo ze-CMC:
I-solubity yamanzi ephezulu.
Izakhiwo ezinhle kakhulu zokuqina nokuzinza.
Kuqiza kahle.
Isicelo esiguquguqukayo ezimbonini ezahlukahlukene.

Okubi kwe-CMC:
Amandla akhawulelwe amafilimu.
Ukuqina okuphansi okuphansi kuqhathaniswa ne-HPMC.
Ingabonisa ukusebenza okuguqukayo ngokuya nge-PH ne-electrolyte okuhlushwa.

Izinzuzo ze-HPMC:
Izakhiwo ezinhle kakhulu zefilimu.
Ukuqina okungcono kakhulu okushisayo.
Inikeza ukunamathela okuthuthukile nokusebenza kwezicelo zokwakha.
Ilungele ukwakheka kwamakhambi okulawulwa.

Okubi kwe-HPMC:
Izindleko eziphakeme ngokuqhathaniswa ne-CMC.
I-Solubity ingahluka ngokuya ngezimo nangezicelo zezicelo.
Ukucutshungulwa kungadinga imishini ethile nemibandela ethile.

5. Ukufaneleka kwezicelo ezithile:

CMC:
Ilungele izinhlelo zokusebenza ezidinga i-solubity yamanzi ephezulu kanye nezakhiwo eziqina, njengokudla nemikhiqizo yokunakekelwa komuntu siqu.
Ilungele izinhlelo zokushisa okuphansi lapho ukuzinza okushisayo akuyona into ebalulekile.
Kusetshenziswa kabanzi ekwakhekeni kwamakhambi lapho kuchithwa khona okusheshayo.

I-HPMC:
Kukhethwe izicelo ezidinga izakhiwo ezinhle kakhulu zefilimu, ezinjengezimbozo namafilimu ezimbonini zokudla kanye nokudla.
Ilungele kahle izicelo zokwakha ngenxa yokunamathela kwayo okuphakeme, ukusebenziseka, kanye nokuqina okushisayo.
Ilungele izinhlelo zokukhishwa kwezidakamizwa ezilawulwayo ezidinga ama-kinetics aqondile.

6. Isiphetho:

Kokubili i-CMC ne-HPMC ziyizinto ezilulekile zokutholwa kwama-cellulose anezakhiwo ezihlukile kanye nezicelo. Ukuzikhethela phakathi kwe-CMC ne-HPMC kuncike kwizidingo ezithile ezinjenge-solubity, i-viscosity, ikhono elakha amafilimu, ukuqina okushisayo, kanye nokucatshangelwa kwezindleko. Ngenkathi i-CMC inikezela nge-solubility yamanzi aphezulu kanye nezindawo ezinhle kakhulu zokuqina, ama-hpmc ama-exlels ekwakhekeni kwamafilimu, ukuqina okushisayo, nokunamathela. Ukuqonda izici ezihlukile zokususwa kwe-cellulose ngayinye kubalulekile ekukhetheni umkhiqizo ofaneleke kakhulu ohlelweni oluthile, uqinisekise ukusebenza okuhle kanye nokusebenza kwezindleko.