Kuyini ukubonakala kwe-hydroxypropylll methylcellulose?

I-Hydroxypropyl Methylcellulose (HPMC) iyi-persener, i-ejenti ye-gelling kanye nefilimu yangaphambili evame ukusetshenziswa ezimbonini zezinto zokwakha ezemithi, zokudla, zokugcoba kanye nokwakha. I-viscosity yayo ingenye yamapharamitha abalulekile athinta ukusebenza kwawo, okuvame ukwehluka ngokuya ngezinto ezifana nokuhlushwa kwesixazululo, uhlobo lwe-solvent, izinga lokushisa kanye nesisindo se-HPMC.

Inani le-viscosity le-HPMC libhekisela ebulilini besixazululo salo ngaphansi kwezimo ezithile, imvamisa kuvezwa kwi-MPA · s (millipascal Seconds). Esimweni se-viscocity se-HPMC, okuhlushwa okuvamile kungu-2% noma 4% solution, futhi izinga lokushisa ngokuvamile lingu-20 ° C noma 25 ° C. Ngokuya ngomkhiqizo kanye nomkhiqizo, i-viscosity ye-HPMC ingasukela kuma-MPA angamakhulu ambalwa ama-MPA'a ayizinkulungwane ezimbalwa.

Lokhu okulandelayo kuyizinto eziphambili ezithinta ukubonakala kwesisombululo se-HPMC:

Isisindo samangqamuzana: Kukhudlwana isisindo se-molecular ye-HPMC, kukhuphuka okubonakalayo kwayo. I-HPMC enesisindo esiphakeme samangqamuzana ingakha ukusebenzisana okwengeziwe kwe-intercoltive kukhambi, ngakho-ke kukhombisa ukubonakala okuphezulu.

I-Hydroxypropyl kanye ne-methyl efakwa esikhundleni se-methyl: kuphakama izinga le-hydroxypropyllls (-h) kanye ne-methyl (-ch₃) esikhundleni sokufakwa esikhundleni, kuphakama i-solubility yamanzi nokuvunywa kwe-HPMC. Ukwanda kwe-hydroxypropyl efakwa esikhundleni sokuthuthukisa ngempumelelo i-solubity ye-HPMC, ngenkathi i-methylation ithuthukisa ukubonakala kwayo.

Ukuhlushwa Isixazululo: Ukuhlulwa kwesisombululo se-HPMC kuthinta ngqo ukubonakala kwayo. Lapho kukhuphuka khona ukugxila, kukhuphuka okukhulu. Ngokuvamile, izixazululo ezinokuhlushwa phakathi kuka-2% no-5% zivame kakhulu, futhi ukubonakala kwezisombululo zokuhlushwa okuphezulu kuzoba ngaphezulu.

I-Solvent: I-HPMC ihlakaze kahle emanzini, ngakho-ke ukubonakala kwayo kuvame ukuhlolwa ngokuya ngezixazululo zamanzi. Kodwa-ke, izinhlobo ezahlukene ze-solvents nazo zingathinta i-solubity kanye nokubonana.

Ukushisa: izinga lokushisa linomthelela omkhulu ekuboneni kwesisombululo se-HPMC. Ngokuvamile, ukwanda kwezinga lokushisa kuzoholela ekunciphiseni ekuvulekeni kwesixazululo ngoba amazinga okushisa aphezulu azosheshisa ukunyakaza kwamangqamuzana futhi akhuphule ukufutheka kwesixazululo.

I-HPMC Viscosity ivame ukusetshenziswa kule mikhakha elandelayo:

Insimu yezemithi: Isetshenziswa njenge-ejenti yokukhishwa kwezidakamizwa, i-tinder tablet, kanye nengxenye yamagobolondo e-capsule. Kungaqinisekisa ukukhishwa kwezidakamizwa ezindlekweni emzimbeni ngokulawula ukubonwa.

Umkhakha Wokudla: Kusetshenziswe njenge-ejenti enkulu kanye ne-gelling, kungathuthukisa ngempumelelo ukunambitheka nokuthungwa kokudla, okufana no-ayisikhilimu, i-jelly, uswidi, njll.

Imboni Yokwakha: Isetshenziswa njenge-readener kanye ne-ejenti yokwakha izinto ezinjengesimende nodaka ukuze kuthuthukiswe uketshezi nokwenza umsebenzi wokwakha.

Imboni yezimonyo: Isetshenziswa emikhiqizweni efana nokhilimu, abahlanza ubuso, izithunzi zamehlo, njll. Ukuhlinzeka nge-viscosity enhle nokuqina.

Lapho ukhetha umkhiqizo ofanele we-HPMC, kubalulekile ukuqonda izici zayo ezithile zokuvuselela, ikakhulukazi izidingo ze-fluidity kanye nokuqina kuzinhlelo zokusebenza ezihlukile. Uma kunesidingo senani elithile le-viscosity le-HPMC ethile, ungabheka imininingwane efanelekile ekucacisweni komkhiqizo noma uyihlole ngensimbi yokulinganisa ye-viscosity.