Uyini umehluko kwinqubo yokukhiqiza phakathi kohlobo lwe-HPMC olubandayo lwamanzi asheshayo nohlobo lokuncibilika okushisayo?

I-HPMC (Hydroxypropyl Methylcellulose) iyinto evame ukusetshenziswa kwe-polymer esetshenziswa kabanzi ekwakheni, emikhakheni, ukudla, amakhemikhali nsuku kanye nezinye izinkambu. Ngokuya nge-solubility yayo emanzini, ingahlukaniswa ngohlobo lwamanzi olubandayo ngokushesha nohlobo olushisayo lokuncibilika. Kunokwehluka okukhulu kwinqubo yokukhiqiza yalezi zinhlobo ezimbili ze-HPMC.

(1), ukucubungula okungavuthiwe kwezinto ezibonakalayo
1.
Ehlelweni lokukhiqiza lamanzi abandayo asheshayo HPMC, izinto ezingavuthiwe kuqala kudingeka zihlelwe. Izinto ezingavuthiwe zihlanganisa i-cellulose, i-methanol, i-propelene oxide, i-methyl chloride, njll. Izinto zokwakha ezivuthiwe zidinga ukuchotshozwa kahle futhi zixutshwe ngesikhathi sokuhlekisa ukuze kuqinisekiswe ukufana kanye nokwanela kokusabela. Ikakhulu, ukwelashwa kwe-cellulose kudinga ukomisa okuqinile nokuchoboza ukufeza ukusatshalaliswa kosayizi abafanelekile.

2. I-Hot Melt Type
I-HOT-MELT HPMC iyafana ne-HPMC esheshayo yamanzi ebandayo ngokuya ngokucutshungulwa okubonakalayo okubonakalayo, kepha inezidingo eziphakeme zokucutshungulwa kweselula. Ngoba i-HPMC eshisayo i-HPMC idinga ukuphendula emazingeni okushisa aphezulu, ubumsulwa nobukhulu bezinhlayiyana ze-cellulose banomthelela omkhulu kwinqubo yokusabela. Ngokuvamile kudingekile ukusebenzisa i-cellulose ehlanzekile ephezulu, futhi ubukhulu bezinhlayiyana kumele bulawulwe ngokuqinile ngesikhathi senqubo yokuchotshozwa.

(2), ukusabela kwe-synthesis
1.
Ukusabela kwe-synthesis kwamanzi abandayo i-HPMC kuvame ukwenziwa emazingeni okushisa aphansi, kuvame ukulawulwa kuma-20-50 degrees Celsius. Ngesikhathi senqubo yokusabela, iselula lokuqala lihlelwe ngaphansi kwezimo ze-alkali ukuhlukana ngezinye zenza amaketanga ama-cellulose ama-cellulose ama-cellulose ama-cellulose Ngemuva kwalokho, abaphendulayo njenge-methanol, i-propellene oxide ne-methyl chloride yengezwa ngaphansi kwezimo ezivusa izimo ukwenza ukusabela kokuthezeka. Yonke inqubo yokuphendula idinga ukulawulwa okuqinile kokushisa kanye ph ukuqinisekisa ukufana nokuqina komkhiqizo.

2. I-Hot Melt Type
Ukusabela kokuhlanganiswa kweHot-Melt HPMC kwenziwa emazingeni okushisa aphezulu, ngokuvamile ama-degree angama-50-80 Celsius noma aphakeme. Inqubo yokuphendula iyafana nohlobo lwamanzi abandayo asheshayo, kepha ngenxa yesilinganiso sokuphendula esisheshayo ngaphansi kwezimo zokushisa eziphakeme, okunembile kokulawulwa kokushisa kanye nesikhathi sokuphendula kuyadingeka. Emazingeni okushisa aphezulu, ukusabela kwe-hydrolysis kanye ne-etherization ye-cellulose kuqediwe ngokwengeziwe, futhi ukusatshalaliswa kwesisindo molecular komkhiqizo kuyunifomu ngokwengeziwe.

(3) Inqubo yokusebenza ngemuva kokusebenza
1.
Ngemuva kokusabela kokuhlanganiswa kwamanzi abandayo i-HPMC esheshayo ye-HPMC, kudingeka uchungechunge lwezinqubo zokusebenza ngemuva. Esokuqala ukusabela kokungathathi hlangothi kokungathathi hlangothi izinto ze-alkali engxube yokusabela. I-FILTRATION NOKUGCINA ZEWENZIWA UKUZE UVUSELE UKUZE UQHAWULEKILE KAKHULU KANYE NEMITHETHO. Isinyathelo sokugcina somile futhi sidilize. Umkhiqizo womile ukulawula okuqukethwe umswakama, bese udilizwa usayizi ofanele wezinhlayiyana ukuthola umkhiqizo ophelile we-HPMC.

2. I-Hot Melt Type
Inqubo yangemva kokwelashwa kwe-HOT-Melt HPMC iyafana ngokuyisisekelo naleyo ye-HPMC esheshayo enamanzi. Kodwa-ke, ngenxa yokushisa okuphezulu okusetshenziswa kwinqubo yokusabela, okuqukethwe umswakama womkhiqizo kuphansi futhi inqubo yokumisa ilula. Ngaphezu kwalokho, i-HOT-MELT HPMC idinga ukunaka kakhulu ukulawula amazinga okushisa okuchoboza ngesikhathi senqubo yokuchoboza ukuvikela ukonakala kokusebenza komkhiqizo ngenxa yokushisa okuphezulu.

(4), ukusebenza kanye nesicelo
I-HPMC enamanzi ebandayo isetshenziswa kabanzi emasimini adinga ukwakheka okusheshayo kwefilimu noma ukuqina, njengezinkomba zokwakha, ama-emulsions, njll ngenxa yokuchithwa kwayo okusheshayo emanzini abandayo. Izidingo zayo zenqubo yokukhiqiza ziphakeme kakhulu, ikakhulukazi ukulawulwa kwezimo zokuphendula emazingeni okushisa aphansi.

I-Hot-Melt HPMC ilungele izinhlelo zokusebenza ngaphansi kwezimo zokushisa eziphakeme, njenge-tile anamathela, i-putty powder, njll., Ngenxa ye-solubility yayo enhle kakhulu emanzini ashisayo. Inqubo yayo yokukhiqiza ilula kakhulu, kepha inezidingo eziphakeme ekuhlanzeni kwezinto zokusetshenziswa okuvuthiwe nokulawulwa kokushisa kokushisa.

Umehluko omkhulu kwinqubo yokukhiqiza phakathi kohlobo lwamanzi abandayo onke nohlobo lwe-HPMC ngumehluko ekushiseni lokuphendula, okuthinta ngqo umehluko ekusebenzeni okubonakalayo okubonakalayo, inqubo yokusetha ukusabela kanye nenqubo yokwelashwa. Uhlobo lwamanzi olubandayo ludinga ukusabela emazingeni okushisa aphansi futhi lunezidingo eziphakeme zokushisa nokulawula i-PH, ngenkathi uhlobo olushisayo luyancipha ekushiseni okuphezulu futhi kukhokha ubumsulwa bezinga lokusetshenziswa. Lezi ezimbili zihlukile nasezinkundleni ezithile zohlelo lokusebenza, futhi ngayinye idlala indima ebalulekile.