Uyini umehluko phakathi kwe-HPMC ne-CMC?

I-HPMC (Hydroxypropyl Methylcellulose) ne-CMC (i-carboxymethyl celtuleose) zombili ezisetshenziswayo ezisetshenziswayo ezisetshenziswayo, ezisetshenziswa kabanzi ekudleni, emikhakheni, ezokwakha kanye nezinye izinkambu.

1. Ukwakheka kwamakhemikhali nendlela yokulungiselela

I-HPMC:
Isakhiwo samakhemikhali: I-HPMC iyindawo eyenziwe nge-polymer ye-polymer etholwe ngokuphendula ngemvelo i-cellulose ene-oxide ye-oxide ne-methyl chloride ngemuva kokwelashwa kwe-alkali.

Iyunithi eliphambili lesakhiwo yindandatho ye-glucose, exhunywe ngamabhondi angama-1,4-β-glucosidic, kanti amanye amaqembu e-hydroxy athathelwa indawo yi-methoxy (-ch₃) ne-hydroxypropyll (-ch₂chohch₃).
Indlela Yokulungiselela: Okokuqala, i-cellulose iphathwa ngesisombululo se-sodium hydroxide ukwakha i-Alkali Cellule

CMC:
Isakhiwo samakhemikhali: I-CMC iyinto etholwa yi-anionic cellulose etholwe ngokuphendula i-cellulose nge-chlororopetic acid ngaphansi kwezimo ze-alkaline.
Uphiko oluphambili lwesakhiwo luyindandatho ye-glucose, exhunywe ngamabhondi angama-1,4-β-β-glucosidic, kanti amanye amaqembu e-hydroxyl athathelwa indawo yi-carboxymethyl (-ch₂cooh).
Indlela yokulungiselela: I-Cellulose iphendula nge-sodium hydroxide ukwakha i-Alkali Cellulose, lapho bese ephendula nge-chlororose acid, bese ekugcineni ingathathi hlangothi, ihlanza futhi iyoma ukuthola i-CMC.

2. Izakhiwo zenyama nezamakhemikhali.

I-Solubity:
I-HPMC: incibilika emanzini abandayo kanye nezinye izixazululo ze-organic, insoluble emanzini ashisayo. Lapho ikhambi lipholile, kungakhiwa ijeli elisobala.
I-CMC: incibilika emanzini abandayo namanzi ashisayo ukwakha ikhambi le-colloidal le-viscous.

I-Viscosity kanye Rheology:
I-HPMC: Inomphumela omuhle wokuqina kanye nokuqina kokumiswa kwesisombululo samanzi, futhi ine-pseudoplastic (i-shear finning) izakhiwo ze-bhe ngokweqiniso.
I-CMC: Inokubonakala okuphezulu nezindawo ezinhle zesimbozo se-rheological kusisombululo samanzi, kukhombisa i-thixotropy (ukuqina lapho kumile, kuncipha lapho ivuselelwa) kanye ne-pseudoplalicity.

3. Izinkambu zohlelo lokusebenza

I-HPMC:
Imboni yokudla: Njengomkhulu, i-Stabilizer, eMulsifier kanye nefilimu yangaphambili, esetshenziswa ku-ayisikhilimu, imikhiqizo yobisi, i-jelly, njll.
Imboni yezemithi: Isetshenziswa njenge-binder, ukuqhelelana ne-ejenti yokukhishwa kanye nokulawulwa kokukhishwa kokulungiselela ithebhulethi.
Izinto zokwakha: ezisetshenziswe ku-cuterswar datar kanye nemikhiqizo ye-gypsum ukwenza ngcono ukugcinwa kwamanzi nokusebenza.
Izimonyo kanye nemikhiqizo yokunakekelwa komuntu siqu: Kusetshenziswa ku-lotion, okhilimu, ama-shampoos kanye nama-gels okugeza, njll., Ukuhlinzeka ngemiphumela yokuqina nokuqina.

CMC:
Imboni yokudla: Njengomkhulu, i-stabilizer kanye ne-emulsifier, esetshenzisiwe ku-jam, jelly, u-ayisikhilimu kanye neziphuzo.
Imboni yezemithi: Isetshenziswa njenge-binder, ukuqhekeka kwamathebhulethi emithi kanye nefilimu yangaphambili yamaphilisi emithi.
Imboni yamaphepha ephaketheni: Isetshenziswa njenge-ejenti yamandla emanzi kanye ne-ejenti ye-survate suling ukuthuthukisa amandla owomile nokuphrinta iphepha.
Imboni yendwangu: Isetshenziswa njenge-ejenti ye-ejenti kanye ne-ejenti yokuqeda ukuthuthukisa amandla futhi icwebezele izindwangu.
Imboni yamakhemikhali yansuku zonke: isetshenziswa njenge-reatriner ne-stabilizer for detergents, amazinyo nemikhiqizo yokunakekelwa kwesikhumba.

4. Ukuvikelwa kwezemvelo nokuphepha

Kokubili i-HPMC ne-CMC yizinto ezingezona ezinobuthi futhi ezingacasuli izinto ze-polymer ezingenakubonwa ngama-enzyme wokugaya emzimbeni womuntu futhi ngokuvamile zibhekwa njengezengezo zokudla eziphephile kanye nama-excipie aphephile. Zisolwa kalula emvelweni futhi zinokungcoliswa okuncane emvelweni.

I-5. Izindleko kanye nokunikezwa kwemakethe

I-HPMC isetshenziswa ikakhulukazi emikhakheni enezidingo eziphezulu zokusebenza ngenxa yenqubo yayo yokulungiselela eyinkimbinkimbi, izindleko eziphezulu zokukhiqiza kanye nentengo ephezulu.

Inqubo yokukhiqiza ye-CMC ilula, izindleko ziphansi, intengo inobuhlobo obukhulu, futhi uhla lwesicelo lubanzi.

Yize i-HPMC ne-CMC yomabili ama-cellulose derivatives, akhombisa izici ezihlukile futhi asebenzisa ngenxa yezinhlaka zawo zamakhemikhali, izakhiwo ze-physichicochemical kanye nezinkundla zohlelo lokusebenza. Ukukhethwa kwalo lapho kutholakala khona iselula okusetshenziswa ngokuvamile kuncike kwizidingo ezithile zesicelo nokucatshangelwa komnotho.