Yini i-viscosity amamaki e-hypromellose?

I-Hypromellose, eyaziwa nangokuthi i-hydroxypropyllylylyllose (HPMC), iyi-polymer etholakala ku-cellulose. Ngenxa yezakhiwo zayo ezisebenzayo, kuvame ukusetshenziswa ezinhlotsheni ezahlukahlukene, kufaka phakathi ama-Pharmaceuticals, ukudla nezimonyo. Impahla ebalulekile ye-Hypromellose ingukuvunywa kwayo, okuhlukahluka ku-grade noma uhlobo lwe-hypromellose olusetshenzisiwe.

I-Hypromellose Piscosiouse Amamanadi avame ukuhlukaniswa ngokwesisindo sawo se-molecular kanye nezinga lokufaka esikhundleni. Isisindo samangqamuzana sithinta ubude be-polymer chain, kanti amazinga okufaka esikhundleni abhekisele ezingeni lokuthi amaqembu we-hydroxypropyl kanye nama-methyl afakwa esikhundleni se-cellulose backbone.

Nawa amanye amabanga okuvunywa ajwayelekile we-Hypromellose nezakhiwo zawo:

1. Ibanga eliphansi lokubona:

Izici: Isisindo esiphansi samangqamuzana, amaketanga afushane we-polymer.
Izicelo: Lawa mabanga asetshenziswa kakhulu njengezixhuma ezinhlangothini zethebhulethi lapho ukubonakala okuphansi kusiza ukugeleza okungcono nokucindezelwa okungcono.

2. Ibanga eliphakathi le-Viscosity:

Izakhiwo: isisindo samangqamuzana aphakathi nendawo, ukulingana phakathi kokuvunywa kanye ne-solubity.
Izicelo: Kusetshenziswe kabanzi kumakhemisi njengoba ama-Matrix amafomu ezinhlelweni zokukhishwa kwezidakamizwa ezilawulwayo, nasembonini yokudla ukuze akhukeze futhi agxile.

3. Ibanga eliphakeme eliphakeme:

Izici: Isisindo esiphakeme samangqamuzana, amaketanga amade we-polymer.
Isicelo: Isetshenziswa ngokujwayelekile kumalungiselelo wokukhulula okuqhubekayo kanye nezixazululo ze-ophthalmic. Bahlinzeka ngamandla we-gel athuthukisiwe nokuvunywa.

4. Izinga lochwepheshe:

Izakhiwo: Izakhiwo zangokwezifiso zezicelo ezithile.
Izicelo: Kuzothuthukiswa amamaki ngokwezifiso ukuze ahlangabezane nezidingo ezithile zezimboni ezahlukahlukene ezinjengezakhi ze-opthalmic, izinhlelo zokusebenza ze-topical nokukhishwa kwezidakamizwa ezilawulwayo.

Kuyaqapheleka ukuthi ukubonakala kuvame ukukalwa kumayunithi we-centipoise (CP) noma imizuzwana ye-millipascal (MPA- s). Ibanga elithile le-viscosity elikhethelwe uhlelo lokusebenza oluthile kuncike kwizimpawu zokusebenza ozifunayo, njengephrofayili yokukhishwa ekwakhiweni kwemithi noma ukuthungwa emikhiqizweni yokudla.

Lapho ukhetha ibanga le-Hypromellose, abakhiqizi babheka izici ezifana nesicelo esihlosiwe, i-viscosity efiselekayo, kanye nokuhambisana nezinye izithako. Ngaphezu kwalokho, amazinga alawulayo nezidingo eziphikisayo kungathonya ukukhethwa kwe-Hypromellose ekunikezelweni kwezidakamizwa nokudla.

Njenganoma yikuphi okubonakalayo, kubalulekile ukulandela imihlahlandlela yezimboni kanye nokucaciswa lapho usebenzisa i-Hypromellose ekuqinisekiseni ikhwalithi yomkhiqizo nokuhambisana namazinga afanele.