Yiziphi izinto ezingavuthiwe ze-HPMC?

I-Hydroxypropyl Methylcellulose (HPMC) iyinhlangano eguquguqukayo enezinhlobonhlobo zezicelo ezimbonini ezahlukahlukene, kubandakanya nemithi, ukwakhiwa, ukudla kanye nezimonyo. Izinto ezingavuthiwe ezisetshenziselwa ukukhiqizwa kwe-HPMC zivela kwizinsizakusebenza zemvelo nezivuselelekayo.

I-HPMC ingukususelwa kwe-cellulose, i-polymer yemvelo etholakala ezindongeni zeseli zezitshalo. Izinto ezivuthiwe ezikhiqizwe yi-HPMC zibandakanya i-cellulose ne-propelene oxide. Izinto zokusetshenziswa kanye nenqubo yokuhlanganiswa kuchazwa ngemininingwane engezansi:

1. I-cellulose:

Umthombo: Izinto eziphambili ezingavuthiwe ze-HPMC ziyi-cellulose, ekhishwe kusuka ku-soni pulp noma ukotini. I-Wood Pulp ingumthombo ovame kakhulu ngenxa yokuchichima kwayo kanye nokusebenza kwezindleko.
Ukwahlukana: Ukuhlukanisa iselula ngezinto ezisetshenziswayo usebenzisa izinqubo ezahlukahlukene zamakhemikhali nezemishini. I-Wood Pulp iphathwa ngamakhemikhali ukususa ukungcola kanye nokukhipha imicu ye-cellulose.

2. I-Phypene oxide:

Umthombo: I-Phylene Oxide iyingxenye ebalulekile yengxenye ye-HPMC yokwenziwa futhi isuselwa ku-propenene, i-petrochemical etholwe ngesikhathi sokucwengeka kawoyela ongahluziwe.
Ukukhiqizwa: I-Propenene Oxide ngokuvamile ikhiqizwa ngenqubo yamakhemikhali ebizwa nge-chlorohydrins noma i-epoxidation. Kule nqubo, i-propelene iphendula nge-chlorine noma nge-hydrogen peroxide ukwakha i-propelene oxide.

3. Ukusabela kwe-methylation:

Ukuthembela: Ukuhlanganiswa kwe-HPMC kufaka phakathi ukusheshisa kwe-cellulose ene-propelene oxide. Le nqubo ibizwa nangokuthi i-methylation, lapho amaqembu e-hydroxypropyl angeniswa khona emhlane we-cellulose.
Ukwelashwa kwe-Alkali: Ukwelapha iselula nge-alkali (imvamisa i-sodium hydroxide) ukwenza kusebenze amaqembu e-hydroxyl. Lokhu kubenza basebenze ngokwengeziwe ngesikhathi sokuphendula okulandelayo nge-oxylene oxide.

4. Degree methylation:

Ukulawula: Lawula izinga le-methylation (DS) ngesikhathi sokuphendula ukuze uzuze izakhiwo ezifiselekayo ze-HPMC. Izinga lokufakwa esikhundleni lithinta i-solubity, ukubonana nezinye izakhiwo zomkhiqizo wokugcina.
I-Hydroxypropylation:

Ukuphendula: I-cellulose ecushiwe bese yenziwa nge-propelene oxide ngaphansi kwezimo ezilawulwayo. Lokhu kuphumela ekufakweni kwamaqembu ama-hydroxypropyl kanye ne-cellulose chain.
Izinga lokushisa nengcindezi: Lawula ngokucophelela izimo zokuphendula, kufaka phakathi izinga lokushisa nengcindezi, ukuqinisekisa ukusebenza kahle kwenqubo nokuqeda ikhwalithi yomkhiqizo.

5. Ukuphazamisa nokugeza:

Ukungathathi hlangothi kwe-acid: Ngemuva kokusabela, umkhiqizo awuthathwa nge-acid ukususa isisekelo ngokweqile.
Ukugeza: I-HPMC iyagezwa ukususa ukungcola, izinto ezingezelelwe, nemikhiqizo. Lesi sinyathelo sibalulekile ukuthola umkhiqizo wokugcina wokuhlanza.

6. Ukomisa:

Ukukhishwa kwamanzi: Isinyathelo sokugcina ukumisa i-HPMC ukususa noma yimuphi umswakama osele. Lokhu kwakha i-HPMC ngefomu le-powder, elingaqhutshwa futhi futhi lisetshenziswe ezinhlobonhlobo zezicelo.

Izinto ezivuthiwe ze-HPMC zibandakanya ikakhulukazi i-cellulose ethathwe kusuka ku-soli pulp noma ukotini we-fiber kanye ne-oxypene oxide ethathwe ku-petrochemical propylene. Inqubo yokuhlanganiswa Ukusebenza okuhlukahlukene kwe-HPMC kuvela esakhiweni sayo esiyingqayizivele samakhemikhali, okwenza kube yisithako esibalulekile emikhiqizweni ehlukahlukene.