Yiziphi izakhiwo zamakhemikhali ze-HPMC Hypromellose?

I-Hypromellose, eyaziwa nangokuthi yi-hydroxypropyll methylcellulose (HPMC), iyi-polymer yokwenziwa ethathwe ku-cellulose. Kusetshenziswa kabanzi kwizimboni zemithi, zokudla kanye nezimonyo njengoba kukhulu, i-emulsifier kanye ne-binder. I-HPMC iyinto engeyona into enobuthi neyodwa ebonakalayo, okwenza kube ukukhetha okuphephile nemvelo.

1. I-solubity yamanzi

I-HPMC iyancibilika emanzini futhi yakha isixazululo esicacile noma esincanyana. I-solubity ye-HPMC incike kwibanga layo lokubona, isisindo samangqamuzana kanye nesilinganiso sokufakwa esikhundleni. I-viscosity ephezulu nama-molecular isisindo amamaki ancibilikayo kunamabanga aphansi. Izinga lokufaka esikhundleni linquma inani le-hydroxypropyl kanye namaqembu we-methyl anamathele emuva kwi-HPMC Cellulose Backbone. Lapho kuphakama izinga lokufaka esikhundleni sokufaka esikhundleni, lehlisa i-solubility yamanzi.

2. Ukuvuselelwa kwamakhemikhali

I-HPMC iyazinza ngamakhemikhali futhi ayisabeli ngamakhemikhali amaningi we-organic kanye nama-inorganic. Kuyamelana ne-alkalis, ama-acid abuthakathaka kanye nezinhlelo eziningi ze-organic. Kodwa-ke, i-HPMC iphendula ngama-acid anamandla kanye nama-oxidizing agents, okuholela ekunciphiseni kwayo kanye nokulahleka kokusebenza. Ngakho-ke, kunconywa ukugwema ukudalula i-HPMC kuma-acid anamandla noma ama-oxidizing agents.

3. Izakhiwo ezenziwe ngefilimu

I-HPMC inezakhiwo ezinhle kakhulu zefilimu futhi ilungele ukuhlanganiswa kwethebhulethi, ukumiswa kokukhishwa okuqhubekayo kanye ne-emvelotion. Ifilimu eyakhiwa yi-HPMC ivumelana nezimo, icacile futhi ibushelelezi. Ifilimu libuye livimbela ukonakaliswa kwesithako esisebenzayo kwithebhulethi noma i-capsule.

4. I-gelelation eshisayo

Ngokuya ngebanga layo le-viscosity, i-HPMC ihlala i-gelation ye-thermal lapho ifudunyezwa emanzini ngaphezu kokushisa okuthile. Izinga lokushisa le-gelation lisukela ku-50 ° C kuya ku-90 ° C. Ijeli elakhiwe yi-HPMC liyalungiswa, okusho ukuthi lingancibilika emuva esimweni se-liquid ngokupholisa. Le mpahla yenza i-HPMC ilungele ukusetshenziswa ekwakhiweni okulawulwa okulawulwayo, ngoba umuthi ungadedelwa emazingeni okushisa athile.

I-5. Izakhiwo ze-Rheological

I-HPMC ibonisa indlela yokuziphatha ye-Pseudoplastic, okusho ukuthi ukubonakala kwayo kunciphisa ngezinga elikhulayo le-shear. Le mpahla yenza i-HPMC ilungele ukusetshenziswa njenge-smighter kanye ne-stabilizer ekudleni kokudla nezimonyo. I-HPMC isetshenziswa futhi njenge-ejenti elisamiswayo ngenxa yokuziphatha kwayo kwe-Thixotropic, okusho ukuthi ukubonakala kwayo kwehla ngaphansi kwengcindezi eqhubekayo ye-shear.

I-HPMC iyinto eguquguqukayo futhi ephephile enezakhiwo ezinhle zamakhemikhali. I-solubility yayo yamanzi, ukuqina kwamakhemikhali, izakhiwo ezakha amafilimu, i-thermogelling kanye nezakhiwo ze-bhercologing zenza kube ukukhetha okuthandwayo ezimbonini ezahlukahlukene. I-HPMC nayo iyabonakala futhi inobungani bemvelo, okwenza kube ukukhetha okuqhubekayo.