Iqhaza le-hydroxypropylllm methylcellulose ku-putty

I-Hydroxypropyl Methylcellulose (HPMC) iyinhlangano eguquguqukayo futhi eguquguqukayo edlala indima ebalulekile ezinhlelweni ezahlukahlukene, kufaka phakathi ukwakhiwa kwama-tutty. I-Putty iyinto esetshenziswa kakhulu ekwakheni nasezisetshenzisweni ezahlukahlukene zezimboni zokugcwalisa, ukubekwa uphawu kanye nezindawo ezibushelelezi.

1. Sibutsetelo se-hydroxypropylllykyl methylcellulose (HPMC):

I-Hydroxypropylmethylcellellose i-cellulose derivative synthession evela ku-cellulose, i-polymer yemvelo etholakala ezindongeni zeseli zezitshalo. Inqubo yokukhiqiza ifaka ukwelapha i-cellulose nge-alkalis naku-ejenti othembisayo. I-HPMC ephumela yi-powder emhlophe noma emhlophe emhlophe encibilikayo emanzini futhi yakha isixazululo esibonakalayo se-viscous.

2. Izakhiwo ze-hydroxypropyllylyll methylcellulose:

Ngaphambi kokuhlola iqhaza le-HPMC ngesi-putty, kuyadingeka ukuqonda izakhiwo ezibalulekile ze-HPMC:

I-Solubinity yamanzi: I-HPMC ngamanzi incanula futhi yakha isixazululo esicacile nesizinzile lapho ixutshwe namanzi. Le mpahla isiza ukufeza ukuvumelana okudingayo ekwakhiweni kwama-tutty.

I-gelal ye-Thermal: I-HPMC ithola inqubo eguqukayo ye-gerlation ye-geral, okusho ukuthi ukubonakala kwayo kukhuphuka lapho kufudunyezwa futhi kuncipha lapho kupholile. Le mpahla ibalulekile ezinhlelweni ze-tutty lapho kushintsha khona izinga lokushisa ngesikhathi sokuxuba nokusebenzisa.

Ukwakheka kwamafilimu: I-HPMC yakha ifilimu emincane, eguquguqukayo lapho isetshenziswa ebusweni. Le mpahla inomthelela ekunamatheleni nasekubumbaneni kukaPuthety, ithuthukise ukusebenza kwayo njengento yokwelashwa komhlaba.

I-Firener: I-HPMC isebenza njengomkhulu ophumelelayo, ukuhlinzeka nge-viscosity edingekayo kanye nokuvumelana nokuzivocavoca kokubeka. Amandla okuqina alawulwayo asakazeka kalula futhi abushelelezi indawo.

3. Iqhaza le-hydroxypropyllylyly methylcellulose ku-putty:

Ukusebenza okwenziwe ngcono: I-HPMC ithuthukisa ukusebenziseka kwe-putty ngokudlulisela ukuthungwa okubushelelezi nokwenzuzo. Izici ezilawulwa zokuqina kanye nokugcinwa kwamanzi zisiza ukusetshenziswa nokusakazeka kwe-putty ezindaweni ezahlukahlukene.

Ukugcinwa kwamanzi: Enye yemisebenzi esemqoka ye-HPMC ekwakhiweni kwama-tutty amandla ayo okugcina amanzi. Lesi sici sivimbela i-Putty ekumiseni ngaphambi kwesikhathi, iqinisekise isikhathi esanele sohlelo lokusebenza, ukwakheka nokuqeda. Ukugcinwa kwamanzi okuthuthukisiwe nakho kusiza ukuthuthukisa ukunamathela kanye nezibopho zokubopha.

Ukunamathelisa kanye nobumbano: I-HPMC igqugquzela ukunamathela ngokwakha ifilimu elincanyana ebusweni be-substrate, ukukhuthaza isibopho phakathi kwe-tutty kanye nezinto ezingaphansi. Ngaphezu kwalokho, izakhiwo ezibumbanayo zosizo lwe-HPMC zithuthukisa amandla aphelele nokuqina kwesicelo se-Putty ngemuva kwesicelo.

Yehlisa i-shrinkage: I-Shrinkage iyinkinga ejwayelekile ekunikezelweni kwama-tutty futhi ingadala imifantu nokungapheleli ebusweni. I-HPMC isiza ukunciphisa i-shrinkage ngokulawula ukuhwamuka kwamanzi ngesikhathi senqubo yokomisa, okuholela ku-putty ezinzile ngokwengeziwe okumelana nokuqhekeka.

Isikhathi Esithuthukisiwe se-Set: Izakhiwo ze-Thermal Gelling ze-HPMC zingalawula isikhathi esibekiwe e-Putty Distreation. Lokhu kubalulekile ukuthola izinhlelo zokusebenza lapho kudingeka khona isikhathi esithile ku-putty ukusetha nokwelashwa.

4. Izinzuzo zokusebenzisa i-hydroxypropylllylyly methylcellulose ku-putty:

I-Verratility: I-HPMC ingafakwa ezinhlobonhlobo zama-tutty wokwakhiwa, okwenza ilungele izinhlelo ezihlukile ezifana nodonga lwe-putty, izinkuni uPutty kanye nodonga lwangaphandle lwamapulangwe.

Ukuqina okuthuthukile: Izakhiwo ezinamathela ezinamathela ezinama-HPMC ezinamathela futhi zinomthelela ekudleni okuhlala isikhathi eside nasekusebenzeni kwe-putty, kunciphisa amathuba okuqhekeka kanye nezinkinga ngokuhamba kwesikhathi.

Ukuvumelana nezinye izengezo: I-HPMC iyahambisana nohlu lwezengezo kanye nama-filler asetshenziswa kakhulu ekwakhiweni kwama-tutty, okuvumela ukwenziwa ngezifiso kwizidingo ezithile zokusebenza.

Ukucatshangelwa Kwezemvelo: Njengokutholwa kwe-cellulose, i-HPMC ngokuvamile kubhekwa njengento enobungane bemvelo. Kuyinto engathandeki futhi ayibangeli ukungcoliswa okuphambili emvelweni.

I-5. Izicelo ngaphandle kukaPutty:

Imboni yezokwakha: Ngaphezu kwe-putty, i-HPMC isetshenziswa kabanzi ezindaweni ezahlukahlukene zokwakha, kufaka phakathi kodumbu, izinamathiseli kanye nokunamathela ngamathayi, isiza ukuthuthukisa ukusebenza, ukugcinwa kwamanzi nokuqina.

I-Pharmaceuticals: I-HPMC isetshenziswa njenge-binder, ukuqhelelana ne-ejenti yamafilimu e-ejenti ekwenziweni kwamakhambi ngenxa yokuthola ukwakheka kwayo kanye nokukhishwa kwezindawo ezilawulwayo.

Imboni yokudla: Embonini yokudla, i-HPMC isetshenziswa njengesikhulu, i-stabilizer kanye ne-emulsifier emikhiqizweni efana namasoso, ama-dessert kanye nezimpahla ezibhakiwe.

6. Isiphetho:

I-Hydroxypropyl Methylcellulose iyinhlangano eguquguqukayo edlala indima ebalulekile ekwakhiweni kwama-tutty. Izakhiwo zayo ezihlukile, kufaka phakathi i-solubity yamanzi, ukugcinwa kwamanzi okushisayo kanye nezakhiwo ezenziwe ngefilimu, zisiza ukuthuthukisa ukuwenza, ukunamathela nokuqina kwe-putty. Njengengxenye esemqoka yezinto zokwakha, i-HPMC iyaqhubeka nokuthola izicelo ezingaphezu kwama-putty ezinhlotsheni ezahlukahlukene, okukhombisa ukuguquguquka kwayo nokubaluleka kwezenzo zanamuhla zokukhiqiza nezokwakha. Ukucwaninga okuqhubekayo kanye nentuthuko emkhakheni we-polymer Science kungaholela ekutheni ama-nento angeziwe azokwandisa uhla lwezicelo zesikhathi esizayo ze-hydroxypropylylyllyllose.