Hpmc methoxy ne-hydroxypropoxy

I-HPMC (HYDROXYPROPYLCELLELLELLelLellulose) iyi-cellulose derivative esetshenziswa njenge-binder, likhulu kanye ne-emulsifier ezimbonini ezahlukahlukene. Iphinde isetshenziswe njenge-excipoint kuma-Pharmaceuticals. I-HPMC iyi-polymer engenamanzi, i-polymer ye-nonion.

Ukukhiqizwa kwe-HPMC kufaka phakathi ukusheshisa kwe-cellulose nge-methyl chloride ne-propelene oxide. Izinga le-methoxy ne-hydroxypropoxy esikhundleni sokufakwa esikhundleni senqubo yokukhiqiza, okuthinta izakhiwo zokugcina zomkhiqizo.

Impahla ebalulekile ye-HPMC yikhono layo lokuthola ama-gels. Ama-gels we-HPMC asetshenziswa kabanzi embonini yokudla njengabakhulu kanye nabazimizayo. Baphinde basetshenziswe njengabakhi be-ejenti abakhishwe emikhakheni ukulawula isilinganiso lapho kukhululwa khona umuthi. Izakhiwo ze-gel ze-HPMC zingashintshwa ngokulungisa izinga lokufaka esikhundleni se-hydroxypropopoxy namaqembu we-methoxy.

Enye impahla ebalulekile ye-HPMC yi-solubility yayo. I-HPMC iyancibilika kalula emanzini, okwenza kube yinto elungele ikhemisi ehamba phambili. Ihambisana futhi namanye ama-Excipie amaningi asetshenziswa embonini yezemithi, okuvumela ukwakheka kwezidakamizwa okulula.

I-HPMC nayo isetshenziswa embonini yezokwakha njenge-binder kanye nesikhulu emikhiqizweni esekwe kuthusi. Ukungeza i-HPMC kwingxube kasimende kuthuthukisa ukusebenza kwayo futhi kunciphisa ukushwabana nokuqhekeka. Iphinde ithuthukise izakhiwo ezigcina amanzi zengxube ye-cemezelo, ngaleyo ndlela yenza ngcono ukusetha isikhathi namandla aphelele womkhiqizo ophelelwe.

Embonini yezokunakekelwa komuntu siqu, i-HPMC isetshenziswa njengesikhudlwana kanye ne-stabilizer ezimotweni kanye nemikhiqizo yokunakekelwa komuntu. Amandla awo okwenza isakhiwo esinjenge-gel

I-HPMC iyisitatimende esisebenzayo esinezicelo ezahlukahlukene ezimbonini ezahlukahlukene. Izakhiwo zayo zingalinganiswa ngokulungisa izinga lokufaka esikhundleni se-hydroxypropoxy namaqembu we-methoxy. Kuyancibilika kalula emanzini, okwenza kube yinto elungele ikhemisi ehamba phambili. Amandla awo okusebenza kwama-gels enza kube wusizo njengomuntu omkhulu nokuqina ekudleni, ekunakekelweni komuntu siqu nezimboni zokwakha. Ukungeza i-HPMC kwingxube kasimende kuthuthukisa ukusebenza kwayo kanye nezakhiwo zokugcina amanzi, okwenza kube namandla futhi kuhlala isikhathi eside. Sekukonke, i-HPMC iyinto ebalulekile eqhubeka nokuthola izinhlelo ezintsha ezimbonini ezahlukahlukene, ngcono ikhwalithi yemikhiqizo nezinqubo.