Ungayihlanganisa kanjani i-hydroxypropylllym methylcellulose?

I-Hydroxypropyl Methylcellulose (HPMC) iyisengezo esiguquguqukayo esetshenziswa kabanzi ekwakhiweni, emicimbini, ekudleni kanye nezinye izinkambu. Inokuqina okuhle, kwakha amafilimu, okuqinisa ukuqina kanye nokufaka izakhiwo. Indlela efanele yokuxuba ibalulekile ukuze uqinisekise ukusebenza kwayo nekhwalithi yomkhiqizo.

1. Ukulungiselela
Ukulungiselela ngokwezinto ezibonakalayo: qiniseka ukusebenzisa i-HPMC esezingeni eliphakeme. Khetha i-viscosity efanelekile kanye nokucaciswa ngokuya ngohlelo lokusebenza oluthile.
Ukulungiswa Kwemishini: I-Mixer Ephakeme Ephakeme, I-Disperser noma i-Morer Ejwayelekile ivame ukusetshenziswa. Imishini kufanele ihlanzeke futhi ingenakungcoliswa.
Ukukhetha kwe-Solvent: I-HPMC ivame ukuncibilika emanzini abandayo, kepha izixazululo ze-organic noma eminye imidiya nazo zingasetshenziswa kwezinye izimo. Ukukhetha i-solvent efanelekile kubalulekile ukuze kube nomphumela wokuxuba kanye nokwenza umkhiqizo wokugcina.

2. Ukuxuba izinyathelo
Ukuhlehlisa: I-HPMC powder kufanele ihlolwe ngaphambi kokususa izigaxa nokungcola ukuqinisekisa ukuhlakazeka okufanayo.

Isengezo se-solvent:
Indlela yokuhlakazeka kwamanzi ebandayo Gwema ukungeza kakhulu ngasikhathi sinye ukuvikela i-agglomeration. Qhubeka uvuse kuze kube yilapho i-powder ihlakazeke ngokuphelele.
Indlela eshisayo yokuhlakazeka kwamanzi: hlanganisa i-hpmc powder namanye amanzi abandayo ukwakha ukumiswa, bese uwathela emanzini afudumele afudunyezwe ku-70-90 ° C. Govuza ngejubane eliphezulu ukuze uncibilike, bese wengeza amanzi abandayo ukuze upholile wokushisa kwegumbi ukuthola isisombululo sokugcina.

Ukuchithwa nokuqina:
Lapho i-HPMC ichithwa emanzini, ukumiswa kuqala kwakhiwa. Njengoba isikhathi sokuvuselela ukukhuphuka futhi izinga lokushisa liyancipha, i-viscosity kancane kancane inyuka kancane ize ichithwe ngokuphelele. Isikhathi sokuchithwa kwesinye isikhathi sithatha imizuzu engama-30 sibe ngamahora ambalwa, kuya nge-viscosity kanye nokuhlushwa kwe-HPMC.
Ukuqinisekisa ukuchithwa okuphelele, ikhambi lingavunyelwa ukuba lime isikhathi esithile (njengabusuku) ukufeza i-viscosity efanele.

Ukulungiswa nokulungiswa:

Uma kunesidingo, izakhiwo zesixazululo zingashintshwa ngokungeza ezinye izithako (ezifana nezilondolozi, izinhlanzi, njll.). Isengezo kufanele senziwe kancane futhi siqinisekise ukusatshalaliswa okufanayo.
Ukuhlunga nokungcolisa:

Ukususa izinhlayiya ezinganqunyelwe kanye nama-bubble amoya, isihlungi noma i-degasser ingasetshenziswa. I-Filtration ingasusa ukungcola, ngenkathi udonsa kusiza ukuthola isixazululo esizinzile.

3. Ukuqapha
Ikhwalithi yamanzi nokushisa: Ikhwalithi yamanzi inethonya elibalulekile ekuchitheni i-HPMC. Kunconywa ukusebenzisa amanzi athambile noma amanzi e-deionized ukugwema ukubheja okubangelwa yi-calcium ne-magnesium emanzini anzima. Izinga lokushisa eliphakeme kakhulu noma eliphansi kakhulu lizothinta i-solubity kanye nomphumela wokuqina we-HPMC futhi kufanele ilawulwe ngaphakathi kwebanga elifanele.

Ijubane elishukumisayo nesikhathi: Ijubane elikhulu kakhulu lingethula inani elikhulu lomoya kanye nama-bubble efomu; Ijubane eliphakeme kakhulu lingabangela ukuxuba okungalingani. Amapharamitha ashukumisayo kufanele alungiswe ngokuya ngemishini ethile nefomula.

Vikela ukufakwa kwe-agglomeralion: Lapho ungeza i-HPMC powder, kufanele ingezwe kancane futhi ngokulinganayo, futhi igcinwe ivuse ukuvimbela ukwakheka kwama-agglomerates. I-powder ingahle ifakwe kumanzi athile abandayo noma umenzeli wokulwa nokwakheka.

Ukugcinwa nokusetshenziswa: Isixazululo esilungiselelwe i-HPMC kufanele sigcinwe esitsheni esivaliwe ukugwema izinga lokushisa eliphakeme. Lapho igcinwe isikhathi eside, isimo sekhambi kufanele sihlolwe njalo ukuvikela ukuhanjiswa kwezulu noma ukuwohloka.

Ukuxuba i-Hydroxypropyllylylylylylyk kudinga ukulawulwa kwenqubo okuqinile nezinqubo zokusebenza ukuze kuqinisekiswe ukusebenza kwayo nomphumela wokugcina kumkhiqizo wokugcina. Ngokukhethwa kwemishini efanelekile, ukusetshenziswa kwe-solvent, indlela yokuxuba kanye nokuphepha, izixazululo zekhwalithi ephezulu ye-HPMC zingalungiswa ukuze kufezeke izidingo zezindawo ezihlukile zohlelo lokusebenza. Ekusebenzeni kwangempela, ukulungiswa kanye nokusebenza kahle kufanele kwenziwe ngokuya ngezimo ezithile zokuthola umphumela omuhle kakhulu wokuxuba.