Uyazi nge-Hypromellose?

IHydroxypropyl Methylcellulose (Inn Igama: I-Hypromellose), futhi yenziwe lula njenge-Hypromellose (Hydroxypropyl Methylcellulose, idonswa njenge-HPMC), yizinhlobonhlobo zezimali ezixubile ezixubile. Kuyinto esetshenziswayo, engasebenzi, i-viscoelastic polymer evame ukusetshenziswa njenge-ophthalmology, noma njenge-excipient noma i-excipoint e-oral yemithi, futhi ivame ukutholakala emikhiqizweni ehlukahlukene yezentengiselwano.

Njengesengezo sokudla, i-hypromellose ingadlala izindima ezilandelayo: i-emulsifier, i-persener, umenzi osomisayo kanye nokufaka esikhundleni se-gelatin yezilwane. Ikhodi yayo (ikhodi ye-e-code) kuCodex Alimentarius yi-E464.

Izakhiwo zamakhemikhali:

Umkhiqizo osuqediwe we-hydroxypropylllylylylylyly i-powder emhlophe noma okuqinile okuqinile okuqinile, futhi usayizi wezinhlayiyana udlula ngesihluthulelo se-80-mesh. Isilinganiso sokuqukethwe kwe-methoxyl kokuqukethwe kwe-hydroxypropyl yomkhiqizo oqediwe kwehlukile, futhi i-viscosity yehlukile, ngakho-ke iba izinhlobo ezahlukene ezenziwa ngokuhlukile. Inezimpawu zokuncibilika emanzini abandayo futhi insoluble emanzini ashisayo afana ne-methyl cellulose, futhi ukumbumbuluzwa kwalo ku-organic solvents kudlula lokho kwamanzi. Ingachithwa nge-anhydrous methanol nase-ethanol, futhi ingachithwa kuma-hydrocarbon ahlangene anjenge-dichloro methane, i-trichloroethane, kanye nezinto eziphilayo ezifana ne-acetone, i-sopropanol ne-diacetone. Lapho ichithwa emanzini, izohlanganisa nama-molecule amanzi ukuze wakhe i-colloid. Kuzinzile ku-acid ne-alkali, futhi akuthinteki ebangeni le-pH = 2 ~ 12. I-Hypromellose, yize kungenjalo anobuthi, kuyavutha futhi kuphendula ngobudlova ngama-oxidizing agents.

I-viscosity yemikhiqizo ye-HPMC inyuka ngokunyuka kokuhlushwa kanye nesisindo se-molecular, futhi lapho izinga lokushisa likhuphuka, ukubonakala kwalo kuqala ukwehla. Lapho kufinyelela emazingeni okushisa athile, ukubonwa kungazelelwe kukhuphuke futhi kwenzeka ukugcwala. ukuphakama kwe. Isixazululo saso samanzi sizinzile emazingeni okushisa asekamelweni, ngaphandle kokuthi kungadilizwa ngama-enzyme, futhi ukubonakala kwayo okujwayelekile akunankinga yengozi. Inezakhiwo ezikhethekile ze-gelalation ye-thermal, izakhiwo ezinhle zokwakha amafilimu kanye nomsebenzi ongaphezulu.

Ukwenza:

Ngemuva kokuthi i-cellulose iphathwa nge-alkali, i-antion ye-alkoxy eyenziwe yi-dislotation yeqembu le-hydroxyl ingangeza i-apylene oxide ukukhiqiza i-hydroxypropylyllyllyllyllyllyllyllyllyl verle Ingakwazi futhi ne-methyl chloride ukukhiqiza i-methyl cellulose ether. I-Hydroxypropylylylylk ikhiqizwa lapho zombili izindlela zokusabela zenziwa ngasikhathi sinye.

Usebenzisa:

Ukusetshenziswa kwe-hydroxypropyllylylylyly kufana nalezinye izipho lezingcingo ze-cellulose. Isetshenziswa kakhulu njenge-dispersant, umenzi we-ejenti osolayo, omkhulu, i-emulsifier, i-stabilizer, nokunamathela emikhakheni ehlukahlukene. Kuphakeme kunezinye izithathane ze-cellulose ngokuya nge-solubity, ukuhlakazwa, ukucaca kanye nokuphikiswa kwe-enzyme.

Embonini yokudla kanye nezemithi, isetshenziswa njengesengezo. Isetshenziswa njenge-adhesive, likhulu, i-distrisant, i-emollient, stabilizer ne-emulsifier. Akunabuthi ubuthi, alikho inani lokudla okunempilo, futhi akukho zinguquko ze-metabolic.

Ngaphezu kwalokho, i-HPMC inezicelo ku-Synthetic Resin Polymerization, ama-petrochemicals, ama-ceramics, amapakethe, isikhumba, izimonyo, izimbotshana, izinto zokwakha namapuleti wokuphrinta.