Umehluko ezicini zomzimba nangamakhemikhali phakathi kwe-HPMC ne-hemc

I-Hydroxypropyl Methylcellulose (HPMC) neHydroxyEthyll Methylcellulose (Hemc) yi-Cellulose Afers esetshenziswa kabanzi emikhakheni ehlukahlukene ngenxa yezakhiwo zazo eziguquguqukayo zenyama kanye namakhemikhali. Yize izinhlaka zazo zamakhemikhali zifana, kunomehluko obalulekile ezizakhiweni zawo ezizenza zilungele izinhlelo zokusebenza ezihlukile.

Isakhiwo se-1.Chical:

Kokubili i-HPMC ne-hemc kususelwa ku-cellulose, i-polymer yemvelo. Umehluko omkhulu ulele ekuhlolweni okunamathiselwe kwi-cellulose backbone. Ku-HPMC, faka esikhundleni se-methyl kanye ne-hydroxypropyl, ngenkathi kuse-hemc, esikhundleni salokho kufaka phakathi i-methylyer ne-hydroxyethylyl. Lokhu kufaka phakathi kungathinta izakhiwo eziphelele ze-cellulose afes.

2. I-Solubity:

Umehluko obalulekile phakathi kwe-HPMC ne-hemc ngokuziphatha kwabo kwe-solubility. I-HPMC ikhombisa i-soubity engcono emanzini abandayo ngokuqhathaniswa ne-hemc. Le mpahla ibalulekile ukuthi izinhlelo zokusebenza ezidinga ukuchithwa okusheshayo noma ukuhlakazwa kwama-polymers, njengasezimboni zokwakha kanye nokwakha.

3. Ukugcinwa kwamanzi:

I-HPMC ngokuvamile inomthwalo ongcono wokugcina amanzi kune-hemc. Le mpahla ibalulekile kuzinhlelo zokusebenza ezifana nezinhlelo ezenzelwe usimende, lapho ukugcinwa kwamanzi kusiza khona ukulawula inqubo ye-hydration futhi uthuthukise ukusebenziseka.

4. Ukushisa kwe-gel:

Izinga lokushisa lama-gelling likushisa lapho isixazululo noma ukuhlakazwa kuguqula kube yijeli. I-HEMC ngokuvamile amafomu emazingeni okushisa aphansi kune-HPMC. Le mpahla ingahle ibe nenzuzo kuzinhlelo zokusebenza ezifana nemikhiqizo yokudla, lapho kungadingeka khona amazinga okushisa aphansi ama-gelling ezimweni ezithile zokucubungula.

Izakhiwo ze-5.Rhelogical:

Kokubili i-HPMC ne-HEMC kufaka isandla ekuziphatheni kwe-mboleko yezixazululo noma ukuhlukaniswa. Kodwa-ke, imiphumela yabo ekuvulekekeni nasekuziphatheni okunciphisekayo kwe-shear kungahluka. I-Hemc ngokuvamile ihlinzeka nge-viscosities ephezulu ekugxileni okuphansi, okwenza kube lula ukuthola izinhlelo ezithile ezidinga izixazululo ezigxile kakhulu.

I-6. Ukwakheka kwefilimu:

I-HPMC ne-hemc ingakha amafilimu amancanyana lapho isetshenziswa ezindaweni. Ngokuya nge-cellulose ether esetshenzisiwe, amafilimu akhombisa izakhiwo ezahlukene. Amafilimu we-HPMC ngokuvamile avumelana nezimo ngokwengeziwe, kanti amafilimu we-hemc ancipha kakhulu. Le mpahla ithinta ukusetshenziswa kwayo ku-Coating, anamathela kanye nezinye izinhlelo zokusebenza ezakha amafilimu.

7. Ukuhambisana nezinye izinhlanganisela:

Ukukhetha phakathi kwe-HPMC ne-hemc nakho kuncike ekuvumelaniseni kwabo namanye amakhompiyutha. Isibonelo, i-HPMC ivame ukuthandwa ngokwakhiwa kwemithi ngenxa yokuhambisana kwayo nezithako ezahlukahlukene ezisebenzayo, kanti i-hemc ingakhethwa ngezinhlelo ezithile ezisuselwa ezingomeni zayo zokuhambisana.

8. Ukuqina okushisayo:

Zombili lezi zimpi ze-cellulose zibonisa ukuqina okuhle okushisayo, kepha amazinga okushisa angcolisa angehluka ngayo. I-HPMC ivame ukuba nokuqina okuphezulu okushisayo kuqhathaniswa ne-hemc. Lesi sici sibalulekile kuzinhlelo zokusebenza lapho ukuvezwa kwamazinga okushisa aphezulu kucatshangelwa khona.

Yize i-HPMC ne-hemc yabelana nge-backmbone evamile ye-cellulose, ukufakwa kwawo kwamakhemikhali athile kuholela ezicini ezihlukile zomzimba nangamakhemikhali. Ukuqonda lo mehluko kubalulekile ekukhetheni i-ether yeselula efanelekile ngohlelo lokusebenza olunikeziwe, uqinisekise ukusebenza okuhle nokusebenza. Ukuzikhethela phakathi kwe-HPMC ne-hemc kuncike kwizidingo ezithile zohlelo lokusebenza, ezisukela emikhakheni yezemithi kanye nezinto zokwakha ekudleni nasekugqokeni.